Article Dans Une Revue Journal of Neuroscience Methods Année : 2024

SEEG electrode shaft affects amplitude and latency of potentials evoked with single pulse electrical stimulation

Résumé

Background Long and thin shaft electrodes are implanted intracerebrally for stereoelectroencephalography (SEEG) in patients with pharmacoresistant focal epilepsies. Two adjacent contacts of one of such electrodes can deliver a train of single pulse electrical stimulations (SPES), and evoked potentials (EPs) are recorded on other contacts. In this study we assess if stimulating and recording on the same shaft, as opposed to different shafts, has an impact on common EP features. New method We leverage the large volume of SEEG data gathered in the F-TRACT database and analyze data from nearly one thousand SEEG implantations in order to verify whether stimulation and recording from the same shaft influence the EP pattern. Results We found that when the stimulated and the recording contacts were located on the same shaft, the mean and median amplitudes of an EP are greater, and its mean and median latencies are smaller than when the contacts were located on different shafts. This effect is small (Cohen’s d ∼ 0.1), but robust (p-value < 10-3) across the SEEG database. Comparison with existing method(s) Our study is the first one to address this question. Due to the choice of commonly used EP features, our method is congruent with other studies. Conclusions The magnitude of the reported effect does not obligate all standard analyses to correct for it, unless they aim at high precision. The source of the effect is not clear. Manufacturers of SEEG electrodes could examine it and potentially minimize the effect in their future products.

Domaines

Fichier principal
Vignette du fichier
Jedynak__SEEG_electrode_shaft__manuscript_revised.pdf (208.72 Ko) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)
Licence

Dates et versions

hal-04885943 , version 1 (14-01-2025)

Licence

Identifiants

Citer

Maciej Jedynak, Anthony Boyer, Manuel Mercier, Blandine Chanteloup-Forêt, Manik Bhattacharjee, et al.. SEEG electrode shaft affects amplitude and latency of potentials evoked with single pulse electrical stimulation. Journal of Neuroscience Methods, 2024, 403, pp.110035. ⟨10.1016/j.jneumeth.2023.110035⟩. ⟨hal-04885943⟩
35 Consultations
87 Téléchargements

Altmetric

Partager

  • More