Article Dans Une Revue British Journal of Pharmacology Année : 2023

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

Stephen Alexander (1) , Arthur Christopoulos (2) , Anthony Davenport (3) , Eamonn Kelly (4) , Alistair Mathie (5) , John Peters (6, 7) , Emma Veale (8, 9) , Jane Armstrong (10) , Elena Faccenda (10) , Simon Harding (10) , Jamie Davies (10) , Maria Pia Abbracchio (11) , George Abraham (3) , Alexander Agoulnik (12) , Wayne Alexander (13) , Khaled Al-Hosaini (14) , Magnus Bäck (15, 16, 17) , Jillian Baker (1) , Nicholas Barnes (18) , Ross Bathgate (19) , Jean‐martin Beaulieu (20) , Annette Beck-Sickinger (21) , Maik Behrens (22) , Kenneth Bernstein (23) , Bernhard Bettler (24, 25) , Nigel Birdsall (26) , Victoria Blaho (27) , Francois Boulay (28) , Corinne Bousquet (29) , Hans Bräuner-Osborne (30) , Geoffrey Burnstock (31) , Girolamo Caló (32) , Justo Castaño (33) , Kevin Catt (34) , Stefania Ceruti (11) , Paul Chazot (35) , Nan Chiang (36) , Bice Chini (37) , Jerold Chun (38) , Antonia Cianciulli (39) , Olivier Civelli (40) , Lucie Clapp (31) , Réjean Couture (41) , Helen Cox (42) , Zsolt Csaba (43) , Claes Dahlgren (44) , Gordon Dent (45) , Steven Douglas (46) , Pascal Dournaud (43) , Satoru Eguchi (47) , Emanuel Escher (48) , Edward Filardo (49) , Tung Fong (50) , Marta Fumagalli (11) , Raul Gainetdinov (51) , Michael Garelja (52) , Marc de Gasparo (53) , Craig Gerard (36) , Marvin Gershengorn (34) , Fernand Gobeil (48) , Theodore Goodfriend (54) , Cyril Goudet (55) , Lukas Grätz (56) , Karen Gregory (2) , Andrew Gundlach (19) , Jörg Hamann (57) , Julien Hanson (58) , Richard Hauger (38) , Debbie Hay (52) , Akos Heinemann (59) , Deron Herr (60) , Morley Hollenberg (61) , Nicholas Holliday (1) , Mastgugu Horiuchi (62) , Daniel Hoyer (63) , László Hunyady (64) , Ahsan Husain (13) , Adriaan Ijzerman (65) , Tadashi Inagami (66) , Kenneth Jacobson (34) , Robert Jensen (34) , Ralf Jockers (43) , Deepa Jonnalagadda (27) , Sadashiva Karnik (67) , Klemens Kaupmann (68) , Jacqueline Kemp (69) , Charles Kennedy (70) , Yasuyuki Kihara (27) , Takio Kitazawa (71) , Pawel Kozielewicz (56) , Hans‐jürgen Kreienkamp (72) , Jyrki Kukkonen (73) , Tobias Langenhan (21) , Dan Larhammar (74) , Katie Leach (2) , Davide Lecca (11) , John Lee (75) , Susan Leeman (76) , Jérôme Leprince (77) , Xaria Li (75) , Stephen Lolait (4) , Amelie Lupp (78) , Robyn Macrae (3) , Janet Maguire (3) , Davide Malfacini (32) , Jean Mazella (79) , Craig Mcardle (4) , Shlomo Melmed (23) , Martin Michel (80) , Laurence Miller (81) , Vincenzo Mitolo (39) , Bernard Mouillac (55) , Christa Müller (82) , Philip Murphy (83) , Jean‐Louis Nahon (84) , Tony Ngo (27) , Xavier Norel (43) , Duuamene Nyimanu (3) , Anne‐marie O’carroll (4) , Stefan Offermanns (85) , Maria Antonietta Panaro (39) , Marc Parmentier (86) , Roger Pertwee (87) , Jean‐philippe Pin (55) , Eric Prossnitz (88) , Mark Quinn (89) , Rithwik Ramachandran (61) , Manisha Ray (27) , Rainer Reinscheid (78) , Philippe Rondard (55) , G. Enrico Rovati (11) , Chiara Ruzza (90) , Gareth Sanger (91) , Torsten Schöneberg (21) , Gunnar Schulte (56) , Stefan Schulz (78) , Deborah Segaloff (49) , Charles Serhan (36) , Khuraijam Dhanachandra Singh (69) , Craig Smith (92) , Leigh Stoddart (1) , Yukihiko Sugimoto (93) , Roger Summers (94) , Valerie Tan (38) , David Thal (94) , Walter Thomas (75) , Pieter Timmermans (95) , Kalyan Tirupula (69) , Lawrence Toll (96) , Giovanni Tulipano (97) , Hamiyet Unal (69) , Thomas Unger (98) , Celine Valant (94) , Patrick Vanderheyden (86) , David Vaudry (99) , Hubert Vaudry (99) , Jean‐pierre Vilardaga (100) , Christopher Walker (101) , Ji Ming Wang (34) , Donald Ward (102) , Hans‐jürgen Wester (22) , Gary Willars (103) , Tom Lloyd Williams (3) , Trent Woodruff (75) , Chengcan Yao (10) , Richard Ye (104)
1 UON - University of Nottingham, UK
2 Monash university
3 CAM - University of Cambridge [Cambridge, UK]
4 University of Bristol [Bristol]
5 Suffolk University
6 Ninewells Hospital and Medical School [Dundee]
7 University of Dundee
8 University of Greenwich
9 University of Kent [Canterbury]
10 The University of Edinburgh
11 UNIMI - Università degli Studi di Milano = University of Milan
12 FIU - Florida International University [Miami]
13 Emory University [Atlanta, GA]
14 KSU - King Saud University [Riyadh]
15 DCAC - Défaillance Cardiovasculaire Aiguë et Chronique
16 KUH - Karolinska University Hospital [Solna, Sweden]
17 CHRU Nancy - Centre Hospitalier Régional Universitaire de Nancy
18 University of Birmingham [Birmingham]
19 The Florey Institute of Neuroscience and Mental Health
20 University of Toronto
21 Leipzig University / Universität Leipzig
22 TUM - Technische Universität Munchen = Technical University Munich = Université Technique de Munich
23 Cedars-Sinai Medical Center
24 Department of Biomedicine [Basel]
25 Biozentrum [Basel, Suisse]
26 The Francis Crick Institute [London]
27 Sanford Burnham Prebys Medical Discovery Institute
28 UGA - Université Grenoble Alpes
29 CRCT - Centre de Recherches en Cancérologie de Toulouse
30 UCPH - Københavns Universitet = University of Copenhagen = Université de Copenhague
31 UCL - University College London [UCL]
32 Unipd - Università degli Studi di Padova = University of Padua
33 Universidad de Córdoba = University of Córdoba [Córdoba]
34 NIH - National Institutes of Health [Bethesda, MD, USA]
35 Durham University
36 Harvard University
37 UNIMIB - Università degli Studi di Milano-Bicocca = University of Milano-Bicocca
38 UC San Diego - University of California [San Diego]
39 UNIBA - Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro
40 UC Irvine - University of California [Irvine]
41 UdeM - Université de Montréal
42 King‘s College London
43 INSERM - Institut National de la Santé et de la Recherche Médicale
44 GU - Göteborgs Universitet = University of Gothenburg
45 Keele University [Keele]
46 University of Pennsylvania [Philadelphia]
47 Temple University [Philadelphia]
48 UdeS - Université de Sherbrooke = University of Sherbrooke [Sherbrooke]
49 University of Iowa [Iowa City]
50 LabCorp
51 SPBU - Saint Petersburg State University
52 University of Otago [Dunedin, Nouvelle-Zélande]
53 MG Consulting Co [Basel]
54 University of Wisconsin-Madison
55 IGF - Institut de Génomique Fonctionnelle
56 Karolinska Institutet = Karolinska Institute [Stockholm]
57 UvA - Universiteit van Amsterdam
58 ULiège - Université de Liège = University of Liège = Universiteit van Luik = Universität Lüttich
59 Universität Graz = University of Graz
60 SDSU - San Diego State University
61 University of Calgary
62 Ehime University [Matsuyama, Japon]
63 University of Melbourne
64 Semmelweis University [Budapest]
65 Universiteit Leiden = Leiden University
66 Vanderbilt University [Nashville]
67 Lerner Research Institute [Cleveland, OH, USA]
68 Novartis Pharma AG
69 Cleveland Clinic
70 University of Strathclyde [Glasgow]
71 RGU - Rakuno Gakuen University [Japan]
72 UHH - Universität Hamburg = University of Hamburg
73 Helsingin yliopisto = Helsingfors universitet = University of Helsinki
74 Uppsala Universitet [Uppsala]
75 UQ [All campuses : Brisbane, Dutton Park Gatton, Herston, St Lucia and other locations] - The University of Queensland
76 BU - Boston University [Boston]
77 NorDic - Neuroendocrine, Endocrine and Germinal Differentiation Communication
78 FSU - Friedrich-Schiller-Universität Jena = Friedrich Schiller University Jena = Université de Iéna [Jena, Germany]
79 CNRS - Centre National de la Recherche Scientifique
80 JGU - Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University
81 Mayo Foundation
82 Universität Bonn = University of Bonn
83 Edge Hill University
84 IPMC - Institut de pharmacologie moléculaire et cellulaire
85 MPI-HLR - Max Planck Institute for Heart and Lung Research
86 ULB - Université libre de Bruxelles = Free University of Brussels
87 University of Aberdeen
88 The University of New Mexico [Albuquerque]
89 MSU - Montana State University
90 UniFE - Università degli Studi di Ferrara = University of Ferrara
91 QMUL - Queen Mary University of London
92 Deakin University [Waurn Ponds]
93 Kumamoto University
94 Monash University [Melbourne]
95 Kosan Biosciences
96 FAU - Florida Atlantic University [Boca Raton]
97 UniBs - Università degli Studi di Brescia = University of Brescia
98 Maastricht University [Maastricht]
99 UNIROUEN - Université de Rouen Normandie
100 PITT - University of Pittsburgh
101 University of Auckland [Auckland]
102 University of Manchester [Manchester]
103 University of Leicester
104 CUHK - The Chinese University of Hong Kong
Stephen Alexander
Arthur Christopoulos
Alistair Mathie
Jane Armstrong
Elena Faccenda
Simon Harding
Jamie Davies
Jean‐martin Beaulieu
Kenneth Bernstein
Paul Chazot
Nan Chiang
Lucie Clapp
Helen Cox
Gordon Dent
Tung Fong
  • Fonction : Auteur
Cyril Goudet
Karen Gregory
Jörg Hamann
Akos Heinemann
Deron Herr
Nicholas Holliday
Daniel Hoyer
Klemens Kaupmann
Charles Kennedy
Dan Larhammar
Katie Leach
Stephen Lolait
Craig Mcardle
Laurence Miller
Christa Müller
Roger Pertwee
Rithwik Ramachandran
Gareth Sanger
Khuraijam Dhanachandra Singh
Leigh Stoddart
Yukihiko Sugimoto
Roger Summers
David Thal
Hamiyet Unal
  • Fonction : Auteur
Celine Valant
Christopher Walker
Donald Ward
Chengcan Yao

Résumé

The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands ( https://www.guidetopharmacology.org ), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.16177 . G protein‐coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

Dates et versions

hal-04858591 , version 1 (29-12-2024)

Identifiants

Citer

Stephen Alexander, Arthur Christopoulos, Anthony Davenport, Eamonn Kelly, Alistair Mathie, et al.. The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. British Journal of Pharmacology, 2023, 180 (S2), pp.S23-S144. ⟨10.1111/bph.16177⟩. ⟨hal-04858591⟩
134 Consultations
0 Téléchargements

Altmetric

Partager

  • More