Nano-objects, their aggregates and their agglomerates are currently used in industry to manufacture materials with advanced functionalities. Their use requires new tools in diverse fields, such as workplace surveillance or process control. Indeed, little is known yet concerning the adverse effects these objects may have on human health and the environment. There is therefore a need to design tools allowing their in situ real-time detection and characterization during the manufacturing process. In this context, Laser-Induced Breakdown Spectroscopy (LIBS) is seen as a potential candidate for these applications. It was applied to the detection of carbon nanotube balls for workplace surveillance and to the compositional analysis of silicon carbide (SiCx) nanopowders for process control. For this latter issue, the so-called calibration-free LIBS analysis based on modelling of the laser-induced plasma emission spectrum proved to be a real asset. A new method for particle analysis has been tested. It consists of trapping particles in a radio-frequency plasma discharge for LIBS analyses. Such an approach presents several advantages further discussed in this chapter.