Can we distinguish intra- and inter-variability with log Jacobian maps derived from brain morphological deformations using pediatric MRI scans? - Archive ouverte HAL
Poster De Conférence Année : 2024

Can we distinguish intra- and inter-variability with log Jacobian maps derived from brain morphological deformations using pediatric MRI scans?

Résumé

Motivation: Importance of analyzing deformation fields derived from both intra- and inter-individual pairs of T1-weighted images which could offer insights into typical and atypical neurodevelopment. Goal(s): We aimed to fine-tune a 3D CNN to classify intra and inter-individual variability based on log Jacobian maps from deformation fields of pediatric longitudinal MRI. Approach: 279 log Jacobian maps of both intra- and inter-individual pairs are extracted using ANTs. A 3D CNN is trained in two ways (overlap and no overlap) for binary classification using 10-fold cross-validation. Results: As expected, the overlap scenario had higher accuracy and F1 score compared to no-overlap, nonetheless both achieving good results. Impact: This project's focus on pediatric MRI scans aims to understand deformations in medical imaging, advancing diagnostic tools. By distinguishing intra and inter-individual variability using log Jacobian-derived deformation patterns, it subsequently aims to model typical neurodevelopment through trajectories for deviation prediction.
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hal-04835398 , version 1 (13-12-2024)

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  • HAL Id : hal-04835398 , version 1

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Andjela Dimitrijevic, Fanny Dégeilh, Benjamin de Leener. Can we distinguish intra- and inter-variability with log Jacobian maps derived from brain morphological deformations using pediatric MRI scans?. ISMRM 2024, May 2024, Singapour, Singapore. , 2024. ⟨hal-04835398⟩
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