Article Dans Une Revue ChemMedChem Année : 2008

Towards a Self‐Adjuvanting Multivalent B and T cell Epitope Containing Synthetic Glycolipopeptide Cancer Vaccine

Résumé

A new generation of synthetic cancer vaccine: the first self-adjuvanting vaccine prototype combining a cluster of B cell epitope, a CD4+ T helper cell epitope, a CD8+ T cell epitope, and an immunoadjuvant has been synthesized by a chemoselective strategy. Vaccination of mice with this molecularly defined construction induces a strong protection against tumors.

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hal-04823512 , version 1 (06-12-2024)

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Olivier Renaudet, Lbachir Benmohamed, Gargi Dasgupta, Ilham Bettahi, Pascal Dumy. Towards a Self‐Adjuvanting Multivalent B and T cell Epitope Containing Synthetic Glycolipopeptide Cancer Vaccine. ChemMedChem, 2008, 3 (5), pp.737-741. ⟨10.1002/cmdc.200700315⟩. ⟨hal-04823512⟩

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