Nowadays, ethers are considered as potential fuels or fuel additives. Here, the oxidation of a series of ethers was undertaken in a jet-stirred reactor at 10 bar in the cool-flame regime. The reacting mixtures were sampled and analyzed using high-resolution mass spectrometry (Orbitrap). Flow injection analyses were performed. Soft ionization (+/-heated electrospray and atmospheric pressure chemical ionization) were used. Numerous products were detected. Among them, chemical formulas corresponding to highly oxygenated molecules and oligomers were observed. A range of graphical tools was employed characterize the oxidation products.