This study critically analyses filtration process modeling in membrane bioreactor (MBR) technology. More specifically, the variety of approaches and assumptions considered within a curated selection of resistance-in-series (RIS) filtration models found in the literature is critically assessed. Aimed to move towards good filtration process modeling practices, the basis for establishing a unified framework rooted in the fundamentals of membrane fouling is defined in this work, considering fouling classifications, process dynamics, and underlying processes used by different authors for elucidating membrane fouling phenomena. Systematically analyzing these factors should be considered as a basic step for efficiently comparing the performance of different models. This involves a detailed examination of the processes applied within each model and their interplay with the involved resistances and fouling types. A lack of homogeneity in RIS-based filtration modeling has been observed. To address this, basic guidelines towards good modeling practices are proposed aimed at balancing model accuracy and complexity. Specifically, seven model processes, six resistances, and three subgroups for types of fouling, further divided into four or five categories are proposed to guide the selection of processes and state variables in the model structure. Hence, this study facilitates the understanding of different approaches to be used during the modeling exercise of membrane filtration processes within the MBR field, not only to enhance the comprehensibility of available filtration models, but also to help the comparison, implementation, and adaptation of available models and the comprehensive development of new ones.