Communication Dans Un Congrès Année : 2024

Exploring the Role of Dipole-Dipole Interactions and Assembly Shape in Magnetic Hyperthermia: Towards Optimized SAR

Résumé

Magnetic hyperthermia is a process that converts electromagnetic energy into heat by applying an external alternating magnetic field to magnetic nanoparticles (MNPs). The efficiency of magnetic hyperthermia is measured by an observable known as the Specific Absorption Rate (SAR), which quantifies the power absorbed by a magnetic assembly subjected to AC magnetic field and therefore re-emitted as heat. Several parameters are crucial for optimizing the SAR to control heat production (1). One of our aims is to clarify the role of DDI in the magnetic hyperthermia process and to determine the conditions under which the SAR is either reduced or enhanced. To achieve this, we employ two complementary approaches. The first approach is a semi-analytical method based on perturbative calculations that is only suitable for low-density samples. Yet, it allows to pinpoint what are the key parameters to tune the SAR. The second approach is Monte Carlo simulations which are used to investigate samples with high concentrations of nanoparticles. Using semi-analytical approaches within the framework of Debye theory (2), we aim to clarify how the assembly's external shape influences SAR. In particular, we explore the effect of DDI strength in different assembly shapes, understanding their role in modifying the hysteresis behavior and heat generation. We also investigate the effect of the intrinsic nanoparticle's properties by combining uniaxial and cubic magnetocrystalline anisotropies as a possible effect of the intrinsic cubic symmetry of the iron oxide NP. By comparing results from semi-analytical methods and Quantied Time Monte Carlo simulations, we aim to identify the critical parameters that synergistically optimize the (SAR). The authors acknowledge the support of the French Agence Nationale de la Recherche (ANR), ANR “NanoHype”, under grant ANR-21-CE09-0043-01 (1) B. Mehdaoui et al . Adv. Funct. Mater. 2011, 21 ; H. Gavilan et al. Chem. Soc. Rev. 50, 11614 (2021); J.G. Ovejero et al. Materials, 14, 6416 (2021). (2) J-L Déjardin et al Journal of Applied Physics, 2017, 121.

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Dates et versions

hal-04769009 , version 1 (06-11-2024)

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  • HAL Id : hal-04769009 , version 1

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Abdelhamid Morjane, François Vernay, Vincent Russier. Exploring the Role of Dipole-Dipole Interactions and Assembly Shape in Magnetic Hyperthermia: Towards Optimized SAR. Journées de la Matière Condensée 2024 (JMC2024), Société Française de Physique; Aix-Marseille Université, Oct 2024, Marseille (13), France. ⟨hal-04769009⟩
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