The structural problems related with excessive vibrations of steel-concrete composite floors due to human rhythmic activities is the main motivation for the development of an analysis methodology supported by design guides and several researches aiming to obtain the dynamic response of a typical steel-concrete composite floor spanning 10 by 10 m when subjected to human rhythmic dynamic loadings. Therefore, this research develops an extensive study based on the use of four different mathematical formulations used for modelling of the human rhythmic actions. Furthermore, it was observed that high levels of annoying vibrations were reached on the investigated floor during the rhythmic activities. Besides, it was verified that the analysed composite floor may be leaded to a very conservative design depending on the choice of the used dynamic loading model. Finally, design considerations related to a more reasonable and economical dynamic loading models used to evaluate the human comfort of composite floors are discussed.