The Mustang District, located in north-west Nepal, is historically known as an important NS corridor following the course of the Kali Gandaki River and linking the Tibetan plateau to the Indian plains. Historical sources describing the region are scarce or even non-existent for periods preceding the 7th century CE. Despite this lack of written sources and the region’s importance for understanding the different dynamics influencing regional trading routes and cultural exchanges, very little archaeological research has been carried out in Mustang. This is partly due to access restrictions as well as local beliefs, rendering archaeological excavations extremely difficult. Recent investigations in Mustang conducted by Marion Poux over the last 5 years have, however, revealed the vast archaeological richness of the Kali Gandaki Valley. These investigations resulted in the identification of about 200 archaeological sites, 30 of which have been radiocarbon dated. In order to better understand the development of early settlement sites in Upper Mustang, but also to better characterize some of these newly identified sites, we have decided to develop a new research program. This paper will focus on the presentation of this project, and the initial results obtained during the 2023 fieldwork campaign. We will also present some of the solutions and methodologies we have put in place in order to elaborate a more detailed chronological framework, as well as developing a better understanding of cultural interactions between Mustang and neighboring regions.