In delay-tolerant networks (DTNs) with uncertain contact plans, the communication episodes and their reliabilities are known a priori. To maximise the end-to-end delivery probability, a bounded network-wide number of message copies are allowed. The resulting multi-copy routing optimization problem is naturally modelled as a Markov decision process with distributed information. In this paper, we provide an in-depth comparison of three solution approaches: statistical model checking with scheduler sampling, the analytical RUCoP algorithm based on probabilistic model checking, and an implementation of concurrent Q-learning. We use an extensive benchmark set comprising random networks, scalable binomial topologies, and realistic ring-road low Earth orbit satellite networks. We evaluate the obtained message delivery probabilities as well as the computational effort. Our results show that all three approaches are suitable tools for obtaining reliable routes in DTN, and expose a trade-off between scalability and solution quality.