Detachment zones represent a meeting point between surface-derived fluids and rocks, potentially forming mineralized systems (e.g., uranium deposits). However, the hydrodynamics and solute transfer in these zones remain poorly understood, with limited knowledge of the role of plutons associated with detachments. To address these gaps, 2D hydrodynamic numerical models were developed. The study employed a strategy to constrain the numerical modelling set-up by considering the impact of topographical gradient and syntectonic magmatic activity. It also conducted a sensitivity analysis on permeability contrast between the detachment and crust domains and traced meteoric fluids into the detachment, discussing their implications on uranium mobility. The outcomes of the study demonstrate that downward fluid percolation from the surface into detachment zones occurs through two possible mechanisms: (1) an elevated topographic profile (>= 3000 m) combined with high detachment permeability (i.e., 100 times higher than crust permeability), (2) the presence of a heat source like synkinematic pluton within the detachment. The latter mechanism was found to be more effective in facilitating the downward percolation of meteoric fluids that maintained their liquid state. Additionally, the study found that secondary faults in the hanging wall stabilize hydrodynamics by concentrating solute flows, creating areas favorable for mineralization.