Article Dans Une Revue Nucleic Acids Research Année : 2019

The RNA workbench 2.0: next generation RNA data analysis

Résumé

Abstract RNA has become one of the major research topics in molecular biology. As a central player in key processes regulating gene expression, RNA is in the focus of many efforts to decipher the pathways that govern the transition of genetic information to a fully functional cell. As more and more researchers join this endeavour, there is a rapidly growing demand for comprehensive collections of tools that cover the diverse layers of RNA-related research. However, increasing amounts of data, from diverse types of experiments, addressing different aspects of biological questions need to be consolidated and integrated into a single framework. Only then is it possible to connect findings from e.g. RNA-Seq experiments and methods for e.g. target predictions. To address these needs, we present the RNA Workbench 2.0 , an updated online resource for RNA related analysis. With the RNA Workbench we created a comprehensive set of analysis tools and workflows that enables researchers to analyze their data without the need for sophisticated command-line skills. This update takes the established framework to the next level, providing not only a containerized infrastructure for analysis, but also a ready-to-use platform for hands-on training, analysis, data exploration, and visualization. The new framework is available at https://rna.usegalaxy.eu , and login is free and open to all users. The containerized version can be found at https://github.com/bgruening/galaxy-rna-workbench.

Dates et versions

hal-04645055 , version 1 (11-07-2024)

Identifiants

Citer

Jörg Fallmann, Pavankumar Videm, Andrea Bagnacani, Bérénice Batut, Maria Doyle, et al.. The RNA workbench 2.0: next generation RNA data analysis. Nucleic Acids Research, 2019, 47 (W1), pp.W511-W515. ⟨10.1093/nar/gkz353⟩. ⟨hal-04645055⟩
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