The hight yield of bioinformatics data, by mass production via sequencing and metagenomics, leads to fascinating perspectives into the virus-vers. The study of viral genomes is primordial in this quest of knowledge allowing to entertain our fundamental scientific curiosity and to answer actual health matter issues at the same time. New actors that can assimilate and interpret all this data is crucial. In response to the growing demand for bioinformatic tools facilitating comprehensive viral genome annotation, we present VazyMolO 2, a revival and enhancement of the original VazyMolO project that ceased in 2011. This revitalized platform addresses the lack of specific knowledge-collection tools in virology by integrating modular elements encompassing phylogeny, genomics, and proteomics. The project aims to harness the intricate interplay between protein structure and biological function, providing a dynamic and efficient solution for annotating new viral genomes. VazyMolO 2, still in early development, also offers analytic tools to visualize viral protein function in a phylogenic point of view in order to scale the reflection on an entire viral family ; a set of intuitive and interactive figures that guide the user thought process ; a database in which annotations come from mainly studies of our team or from other critical findings. Through this multidimensional approach, VazyMolO 2 bridges the gap in viral genome annotation, empowering researchers with a versatile and user-friendly tool.