Computational Models of Astrocyte Function at Glutamatergic Synapses - Archive ouverte HAL Accéder directement au contenu
Chapitre D'ouvrage Année : 2024

Computational Models of Astrocyte Function at Glutamatergic Synapses

Résumé

At tripartite synapses, astrocytes are in close contact with neurons and contribute to various functions, from synaptic transmission, maintenance of ion homeostasis, and glutamate uptake to metabolism. However, disentangling the precise contribution of astrocytes to those phenomena and the underlying biochemical mechanisms is remarkably challenging. This notably results from their highly ramified morphology, the nanoscopic size of the majority of astrocyte processes, and the poorly understood information encoded by their spatiotemporally diverse calcium signals. This book chapter presents selected computational models of the involvement of astrocytes in glutamatergic transmission. The goal of this chapter is to present representative models of astrocyte function in conjunction with the biological questions they can investigate.
Fichier sous embargo
Fichier sous embargo
1 11 11
Année Mois Jours
Avant la publication
vendredi 10 avril 2026
Fichier sous embargo
vendredi 10 avril 2026
Connectez-vous pour demander l'accès au fichier

Dates et versions

hal-04541189 , version 1 (10-04-2024)
hal-04541189 , version 2 (10-04-2024)
hal-04541189 , version 3 (23-04-2024)

Identifiants

Citer

Kerstin Lenk, Audrey Denizot, Barbara Genocchi, Ippa Seppälä, Marsa Taheri, et al.. Computational Models of Astrocyte Function at Glutamatergic Synapses. Maria Kukley. New Technologies for Glutamate Interaction: Neurons and Glia, 2780, Springer US, pp.229-263, 2024, Neuromethods, ⟨10.1007/978-1-0716-3742-5_11⟩. ⟨hal-04541189v2⟩
0 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More