This article tackles two major problem settings for interpretability of audio processing networks, post-hoc and by-design interpretation. For post-hoc interpretation, we aim to interpret decisions of a network in terms of high-level audio objects that are also listenable for the end-user. This is extended to present an inherently interpretable model with high performance. To this end, we propose a novel interpreter design that incorporates non-negative matrix factorization (NMF). In particular, an interpreter is trained to generate a regularized intermediate embedding from hidden layers of a target network, learnt as time-activations of a pre-learnt NMF dictionary. Our methodology allows us to generate intuitive audio-based interpretations that explicitly enhance parts of the input signal most relevant for a network's decision. We demonstrate our method's applicability on a variety of classification tasks, including multi-label data for real-world audio and music.