Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming

Frédérik Oger; Maeva Moreno; Mehdi Derhourhi; Bryan Thiroux; Lionel Berberian; Cyril Bourouh; Emmanuelle Durand; Souhila Amanzougarene; Alaa Badreddine; Etienne Blanc; Olivier Molendi-Coste; Laurent Pineau; Gianni Pasquetti; Laure Rolland; Charlène Carney; Florine Bornaque; Emilie Courty; Céline Gheeraert; Jérôme Eeckhoute; David Dombrowicz; Julie Kerr-Conte; François Pattou; Bart Staels; Philippe Froguel; Amélie Bonnefond; Jean-Sébastien Annicotte

doi:10.1016/j.isci.2023.107231

Journal Articles iScience Year : 2023

Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming

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Frédérik Oger

Function : Author

Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283

Maeva Moreno

Function : Author

Mehdi Derhourhi

Function : Author

Bryan Thiroux

Function : Author

Lionel Berberian

Function : Author

Cyril Bourouh

Function : Author

Emmanuelle Durand

Function : Author

Souhila Amanzougarene

Function : Author

Alaa Badreddine

Function : Author

Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283

Etienne Blanc

Function : Author

Olivier Molendi-Coste

Function : Author

Laurent Pineau

Function : Author

Gianni Pasquetti

Function : Author

Laure Rolland

Function : Author

Charlène Carney

Function : Author

Florine Bornaque

Function : Author

Emilie Courty

Function : Author

Céline Gheeraert

Function : Author

Jérôme Eeckhoute

Function : Author

David Dombrowicz

Function : Author

Julie Kerr-Conte

Function : Author

François Pattou

Function : Author
PersonId : 758667
ORCID : 0000-0001-8388-3766
IdRef : 074750364

Bart Staels

Function : Author

Philippe Froguel

Function : Author

Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283

Amélie Bonnefond

Function : Author
PersonId : 1305499
IdHAL : amelie-bonnefond
ORCID : 0000-0001-9976-3005

Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283

Jean-Sébastien Annicotte

Function : Author
PersonId : 756470
IdHAL : jean-sebastien-annicotte
ORCID : 0000-0002-2109-4849
IdRef : 086245902

Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167

Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283

Université de Lille

Institut Pasteur de Lille

Centre Hospitalier Régional Universitaire [CHU Lille]

Institut National de la Santé et de la Recherche Médicale

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Life Sciences [q-bio]

Amelie Bonnefond : Connect in order to contact the contributor

https://hal.science/hal-04528661

Submitted on : Monday, April 1, 2024-11:04:57 PM

Last modification on : Thursday, October 3, 2024-10:57:15 AM

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hal-04528661 , version 1 (01-04-2024)

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HAL Id : hal-04528661 , version 1
DOI : 10.1016/j.isci.2023.107231

Cite

Frédérik Oger, Maeva Moreno, Mehdi Derhourhi, Bryan Thiroux, Lionel Berberian, et al.. Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming. iScience, 2023, 26 (7), pp.107231. ⟨10.1016/j.isci.2023.107231⟩. ⟨hal-04528661⟩

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Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming

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