Do smoking abstinence periods among pregnant smokers improve birth weight? A secondary analysis of a randomised, controlled trial - Archive ouverte HAL Access content directly
Journal Articles BMJ Open Year : 2024

Do smoking abstinence periods among pregnant smokers improve birth weight? A secondary analysis of a randomised, controlled trial

Abstract

Objectives: Maternal smoking during pregnancy is associated with low birth weight (LBW). Reduction of cigarette consumption does not seem to improve birth weight but it is not known whether implementation of periods of smoking abstinence improves it. We assessed whether the number of 7-day periods of smoking abstinence during pregnancy may help reduce the number of newborns with LBW. Design and setting: Secondary analysis of a randomised, controlled, multicentre, smoking cessation trial among pregnant smokers. Participants: Pregnant women were included at <18 weeks of gestational age and assessed at face-to-face, monthly visits. Data of 407 singleton live births were analysed. Primary outcome measure: Newborns with low birth weight. Results: 40 and 367 newborns were born with and without LBW, respectively. Adjusted for all available confounders, 3 or more periods of at least 7 days' smoking abstinence during pregnancy was associated with reduced likelihood of LBW compared with no abstinence periods (OR = 0.124, 95% CI 0.03 to 0.53, p = 0.005). Reduction of smoking intensity by at least 50% was not associated with birth weight. Conclusion: Aiming for several periods of smoking abstinence among pregnant smokers unable to remain continuously abstinent from smoking may be a better strategy to improve birth weight than reducing cigarette consumption.
Fichier principal
Vignette du fichier
e082876.full.pdf (285.77 Ko) Télécharger le fichier
Origin Publisher files allowed on an open archive
Licence

Dates and versions

hal-04521664 , version 1 (17-06-2024)

Licence

Identifiers

Cite

Ivan Berlin, Léontine Goldzahl, Florence Jusot, Noémi Berlin. Do smoking abstinence periods among pregnant smokers improve birth weight? A secondary analysis of a randomised, controlled trial. BMJ Open, 2024, 14 (3), pp.e082876. ⟨10.1136/bmjopen-2023-082876⟩. ⟨hal-04521664⟩
32 View
1 Download

Altmetric

Share

Gmail Mastodon Facebook X LinkedIn More