Functional respiratory complaints among COVID-19 survivors: a prospective cohort study - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue ERJ Open Research Année : 2023

Functional respiratory complaints among COVID-19 survivors: a prospective cohort study

Résumé

Background Dyspnoea is a common persistent symptom after COVID-19. Whether it is associated with functional respiratory disorders remains unclear. Methods We assessed the proportion and characteristics of patients with “functional respiratory complaints” (FRCs) (as defined by Nijmegen Questionnaire >22) among 177 post-COVID-19 individuals who benefited from outclinic evaluation in the COMEBAC study ( i.e. , symptomatic and/or intensive care unit (ICU) survivors at 4 months). In a distinct explanatory cohort of 21 consecutive individuals with unexplained post-COVID-19 dyspnoea after routine tests, we also analysed the physiological responses to incremental cardiopulmonary exercise testing (CPET). Findings In the COMEBAC cohort, 37 patients had significant FRCs (20.9%, IC95: 14.9–26.9). The prevalence of FRCs ranged from 7.2% (ICU patients) to 37.5% (non-ICU patients). The presence of FRCs was significantly associated with more severe dyspnoea, lower 6-min walk distance, more frequent psychological and neurological symptoms (cognitive complaint, anxiety, depression, insomnia and post-traumatic stress disorders) and poorer quality of life (all p<0.01). In the explanatory cohort, seven out of 21 patients had significant FRCs. Based on CPET, dysfunctional breathing was identified in 12 out of 21 patients, five out of 21 had normal CPET, three out of 21 had deconditioning and one out of 21 had evidence of uncontrolled cardiovascular disease. Interpretation FRCs are common during post-COVID-19 follow-up, especially among patients with unexplained dyspnoea. Diagnosis of dysfunctional breathing should be considered in those cases.
Fichier principal
Vignette du fichier
00063-2023.full.pdf (1.24 Mo) Télécharger le fichier
Origine Fichiers éditeurs autorisés sur une archive ouverte
Licence

Dates et versions

hal-04519641 , version 1 (04-06-2024)

Licence

Identifiants

Citer

Antoine Beurnier, Laurent Savale, Xavier Jaïs, Romain Colle, Tai Pham, et al.. Functional respiratory complaints among COVID-19 survivors: a prospective cohort study. ERJ Open Research, 2023, 9 (3), pp.00063-2023. ⟨10.1183/23120541.00063-2023⟩. ⟨hal-04519641⟩
10 Consultations
1 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More