Diagnostic utility of T2*-weighted GRE in migraine with aura attack. The cortical veins sign
Chloe Hirtz
(1)
,
Gilles Adam
(1)
,
Nicolas Raposo
(1)
,
Nelly Fabre
(2)
,
Anne Ducros
(3, 4)
,
Lionel Calviere
(1)
,
Vanessa Rousseau
(5)
,
Jean François Albucher
(6)
,
Jean-Marc Olivot
(1)
,
Fabrice Bonneville
(1)
,
Alain Viguier
(1)
Nelly Fabre
- Fonction : Auteur
- PersonId : 1366508
- ORCID : 0000-0002-2971-6120
Anne Ducros
- Fonction : Auteur
- PersonId : 760719
- ORCID : 0000-0001-5560-5013
- IdRef : 087623986
Jean François Albucher
- Fonction : Auteur
- PersonId : 1366738
- IdRef : 270257136
Jean-Marc Olivot
- Fonction : Auteur
- PersonId : 1199283
- ORCID : 0000-0003-2027-2276
- IdRef : 109426452
Alain Viguier
- Fonction : Auteur
- PersonId : 1366509
- ORCID : 0000-0002-0324-3783
Résumé
Objective: To evaluate the frequency, distribution, and clinical associations of the dilated appearance of cerebral cortical veins, termed cortical veins sign on T2*-weighted gradient recalled-echo (T2*-GRE) in the acute setting of migraine with aura attack in adult patients. Methods: We conducted a retrospective analysis of 60 consecutive patients admitted for acute neurological symptoms with a final diagnosis of migraine with aura (42%) or probable migraine with aura (58%) who underwent emergency brain magnetic resonance imaging and 60 non-migrainous control adults. The cortical veins sign was defined as a marked hypo-intensity and/or an apparent increased diameter of at least one cortical vein. We examined the prevalence, the spatial distribution, and the associations of cortical veins sign with clinical characteristics of migraine with aura. Results: We detected the cortical veins sign in 25 patients (42%) with migraine with aura, compared to none in the control group ( p < 0.0001). The spatial distribution of cortical veins sign was characterised by the predominantly bilateral and posterior location. Presence of cortical veins sign was associated with increased severity of aura ( p = 0.05), and shorter delay to MRI ( p = 0.02). Conclusion: In the setting of acute neurological symptoms, the presence of cortical veins sign is frequent in patients with migraine with aura and can be detected with good reliability. This imaging marker may help clinicians identify underlying migraine with aura.
Format du dépôt | Fichier |
---|---|
Type de dépôt | Article dans une revue |
Titre |
en
Diagnostic utility of T2*-weighted GRE in migraine with aura attack. The cortical veins sign
|
Résumé |
en
Objective: To evaluate the frequency, distribution, and clinical associations of the dilated appearance of cerebral cortical veins, termed cortical veins sign on T2*-weighted gradient recalled-echo (T2*-GRE) in the acute setting of migraine with aura attack in adult patients. Methods: We conducted a retrospective analysis of 60 consecutive patients admitted for acute neurological symptoms with a final diagnosis of migraine with aura (42%) or probable migraine with aura (58%) who underwent emergency brain magnetic resonance imaging and 60 non-migrainous control adults. The cortical veins sign was defined as a marked hypo-intensity and/or an apparent increased diameter of at least one cortical vein. We examined the prevalence, the spatial distribution, and the associations of cortical veins sign with clinical characteristics of migraine with aura. Results: We detected the cortical veins sign in 25 patients (42%) with migraine with aura, compared to none in the control group ( p < 0.0001). The spatial distribution of cortical veins sign was characterised by the predominantly bilateral and posterior location. Presence of cortical veins sign was associated with increased severity of aura ( p = 0.05), and shorter delay to MRI ( p = 0.02). Conclusion: In the setting of acute neurological symptoms, the presence of cortical veins sign is frequent in patients with migraine with aura and can be detected with good reliability. This imaging marker may help clinicians identify underlying migraine with aura.
|
Auteur(s) |
Chloe Hirtz
1
, Gilles Adam
1
, Nicolas Raposo
1
, Nelly Fabre
2
, Anne Ducros
3, 4
, Lionel Calviere
1
, Vanessa Rousseau
5
, Jean François Albucher
6
, Jean-Marc Olivot
1
, Fabrice Bonneville
1
, Alain Viguier
1
1
Département Neurologie [CHU Toulouse]
( 547851 )
- Hôpital Pierre-Paul Riquet,
Place du Docteur Baylac - TSA 40031 - 31059 Toulouse cedex 9,
3e étage - hall B
- France
2
GAFL -
Génétique et Amélioration des Fruits et Légumes
( 1002097 )
- INRAE Domaine Saint-Maurice 67 allée des chênes CS60094 84143 MONTFAVET CEDEX
- France
3
Hôpital Gui de Chauliac [CHU Montpellier]
( 306503 )
- Centre Hospitalier Universitaire Hôpital Saint Eloi, 80 Av. Augustin Fliche, 34295 Montpellier
- France
4
L2C -
Laboratoire Charles Coulomb
( 1100677 )
- 1 place Eugène Bataillon Université Montpellier 34095 Montpellier Cedex 5
- France
5
CIC 1436 -
Centre d'investigation clinique de Toulouse
( 259708 )
- Pavillon Riser - 1er étage - Place du Dr Baylac - TSA 40031 - 31059 Toulouse Cedex 9 ;
CHU Purpan - Hôpital Pierre Paul Riquet - Hall D 2ième étage - Place du Dr Baylac - TSA40031 - 31059 Toulouse Cedex 9
- France
6
ToNIC -
Toulouse NeuroImaging Center
( 521838 )
- CHU PURPAN - Pavillon Baudot - Place du Dr Baylac 31024 TOULOUSE - Cedex 3
- France
|
Public visé |
Scientifique
|
Langue du document |
Anglais
|
Licence |
Paternité - Pas d'utilisation commerciale
|
Nom de la revue |
|
Date de publication |
2022-07
|
Volume |
42
|
Numéro |
8
|
Page/Identifiant |
730-738
|
Vulgarisation |
Non
|
Comité de lecture |
Oui
|
Audience |
Internationale
|
Date de publication électronique |
2022-03-18
|
Domaine(s) |
|
Financement |
|
Mots-clés (Mesh) |
|
Mots-clés |
en
Cerebral veins, MRI, migraine aura
|
DOI | 10.1177/03331024221076484 |
Pubmed Id | 35301873 |
UT key WOS | 000773085500001 |
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hirtz-et-al-2022-diagnostic-utility-of-t2 -weighted-gre-in-migraine-with-aura-attack-the-cortical-veins-sign.pdf ( 668.74 Ko
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