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Article Dans Une Revue European Annals of Otorhinolaryngology, Head and Neck Diseases Année : 2024

Dangers and therapeutic difficulties of intracranial hemangioma in infants: A CARE case report

Léa Fath
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François Simon
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Raphaël Levy
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Olivia Boccara
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Vincent Couloigner
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Résumé

Introduction: Description of neurological complications induced by intracranial hemangioma in infants and by the initiation of beta-blocker treatment (propranolol). Observation: A 2-month-old infant was referred for grade 5 non-congenital unilateral peripheral facial palsy. Work-up revealed ipsilateral profound hearing loss and two intracranial hemangiomas: one in the ipsilateral internal auditory canal (IAC), the other in the cerebellum opposite the nodule of vermis. Initial treatment with a beta-blocker (propranolol 1mg/kg/day for 1month, then 3mg/kg/day) resulted in disappearance of symptoms and regression of lesions within 8weeks. At 20months after introduction of maintenance therapy (propranolol 3mg/kg/day), two asthma attacks occurred, leading to initiation of fluticasone and continuation of the beta-blocker. Thirty months after discontinuation of treatment, no further progression was noted. Discussion: Unilateral facial palsy in an infant suggests a number of diagnoses. MRI revealed IAC hemangioma. The choice of dosage and duration of treatment was based on a review of the literature and a strategy defined in multidisciplinary consultation. Keywords: Asthma; Beta-blockers; Hemangioma; Peripheral facial palsy.
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hal-04500360 , version 1 (11-03-2024)

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Léa Fath, François Simon, Raphaël Levy, Olivia Boccara, Vincent Couloigner. Dangers and therapeutic difficulties of intracranial hemangioma in infants: A CARE case report. European Annals of Otorhinolaryngology, Head and Neck Diseases, 2024, in press, ⟨10.1016/j.anorl.2024.02.001⟩. ⟨hal-04500360⟩
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