This article addresses the probabilistic nature of fatigue life in structures subjected to cyclic loading with variable amplitude. Drawing on the formalisation of Miner's cumulative damage rule that we introduced in the recent article [Cartiaux, Ehrlacher, Legoll, Libal and Reygner, Prob. Eng. Mech. 2023], we apply our methodology to estimate the survival probability of an industrial structure using experimental data. The study considers both the randomness in the initial state of the structure and in the amplitude of loading cycles. The results indicate that the variability of loading cycles can be captured through the concept of deterministic equivalent damage, providing a computationally efficient method for assessing the fatigue life of the structure. Furthermore, the article highlights that the usual combination of Miner's rule and of the weakest link principle systematically overestimates the structure's fatigue life. On the case study that we consider, this overestimation reaches a multiplicative factor of more than two. We then describe how the probabilistic framework that we have introduced offers a remedy to this overestimation.