Article Dans Une Revue Journal of Hepatology Année : 2017

CD44 is a key player in non-alcoholic steatohepatitis

Résumé

Cluster of differentiation (CD)44 regulates adipose tissue inflammation in obesity and hepatic leukocyte recruitment in a lithogenic context. However, its role in hepatic inflammation in a mouse model of steatohepatitis and its relevance in humans have not yet been investigated. We aimed to evaluated the contribution of CD44 to non-alcoholic steatohepatitis (NASH) development and liver injury in mouse models and in patients at various stages of non-alcoholic fatty liver disease (NAFLD) progression.

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Dates et versions

hal-04496710 , version 1 (08-03-2024)

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Stéphanie Patouraux, Déborah Rousseau, Stéphanie Bonnafous, Cynthia Lebeaupin, Carmelo Luci, et al.. CD44 is a key player in non-alcoholic steatohepatitis. Journal of Hepatology, 2017, 67 (2), pp.328-338. ⟨10.1016/j.jhep.2017.03.003⟩. ⟨hal-04496710⟩
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