lncRNA : A new danger for genome integrity
Résumé
Many factors affect the genesis of chromosomal aberrations in cells. In this issue of the International Journal of Cancer, Demin et al. describe a long non-coding RNA CASTL (chromosomal aberrations stimulating lncRNA) that facilitates CCDC6-RET fusion (inv(10)(q11;q21)) 1. Expression of CASTL1 is cell-type specific and can account for the appearance of CCDC6-RET fusion only in specific cell types.
Domaines
Sciences du Vivant [q-bio]
Origine : Fichiers produits par l'(les) auteur(s)