Towards More Predictive, Physiological and Animal-free In Vitro Models: Advances in Cell and Tissue Culture 2020 Conference Proceedings
Bhumika Singh
(1)
,
Mohamed Essameldin Abdelgawad
(2)
,
Zulfiqur Ali
(3)
,
Jarrod Bailey
(4)
,
Elisa Budyn
(5)
,
Prospero Civita
(6)
,
Martin J.D. Clift
(7)
,
John Connelly
(8)
,
Samuel Constant
(9)
,
Marius Hittinger
(10)
,
Helena Kandarova
(11)
,
Victoria Rosalind Kearns
(12)
,
Tony Kiuru
(13)
,
Tomasz Kostrzewski
(14)
,
Sebastian Kress
(15)
,
Victoria Marsh Durban
(16)
,
Claus-Michael Lehr
(17)
,
Hayley Mcmillan
(18)
,
Julia Katharina Metz
(17)
,
Vivian Monteban
(19)
,
Dania Movia
(20)
,
Catia Neto
(7)
,
Carla Owen
(21)
,
Lauri Paasonen
(22)
,
Geoffrey John Pilkington
(6)
,
Kerri Anne Palmer
(6)
,
Karen Pilkington
(23)
,
Adriele Prina-Mello
(24)
,
Clive Roper
(25)
,
Jonathan Sheard
(26)
,
Sheree Smith
(20)
,
Janette Ellen
(25)
,
Ipsita Roy
(26)
,
Melissa Anne Tutty
(20)
,
Eirini Velliou
(27)
,
John Malcolm Wilkinson
(28)
1
Kirkstall
2 Helwan University [Caire]
3 Teesside University
4 Center for Contemporary
5 ENS Paris Saclay - Ecole Normale Supérieure Paris-Saclay
6 University of Portsmouth
7 Cardiff University
8 Swansea University
9 QMUL - Queen Mary University of London
10 Pharmbiotec Research and Development GmbH
11 SAS - Slovak Academy of Sciences
12 University of Liverpool
13 UPM-Kymmene Corporation
14 CN Bio Innovations
15 University of Natural Resources and Life Science
16 Cellesce Limited
17 UKS - Saarland University Hospital
18 QUB - Queen's University [Belfast]
19 SABEU GmbH & Co. KG
20 Trinity College Dublin
21 Animal Free Research UK
22 University of Aberdeen
23 Roper Toxicology Consulting Limited
24 Leeds Beckett University
25 Safer Medicines
26 University of Sheffield [Sheffield]
27 UCL - University College of London [London]
28 Technology for Industry
2 Helwan University [Caire]
3 Teesside University
4 Center for Contemporary
5 ENS Paris Saclay - Ecole Normale Supérieure Paris-Saclay
6 University of Portsmouth
7 Cardiff University
8 Swansea University
9 QMUL - Queen Mary University of London
10 Pharmbiotec Research and Development GmbH
11 SAS - Slovak Academy of Sciences
12 University of Liverpool
13 UPM-Kymmene Corporation
14 CN Bio Innovations
15 University of Natural Resources and Life Science
16 Cellesce Limited
17 UKS - Saarland University Hospital
18 QUB - Queen's University [Belfast]
19 SABEU GmbH & Co. KG
20 Trinity College Dublin
21 Animal Free Research UK
22 University of Aberdeen
23 Roper Toxicology Consulting Limited
24 Leeds Beckett University
25 Safer Medicines
26 University of Sheffield [Sheffield]
27 UCL - University College of London [London]
28 Technology for Industry
Mohamed Essameldin Abdelgawad
- Fonction : Auteur
- PersonId : 804724
- ORCID : 0000-0002-7147-8381
Elisa Budyn
- Fonction : Auteur
- PersonId : 15543
- IdHAL : elisa-budyn
- ORCID : 0000-0002-8427-4572
- IdRef : 225253364
Tomasz Kostrzewski
- Fonction : Auteur
- PersonId : 1358482
- ORCID : 0000-0001-6309-628X
Adriele Prina-Mello
- Fonction : Auteur
- PersonId : 1358484
- ORCID : 0000-0002-4371-2214
Sheree Smith
- Fonction : Auteur
- PersonId : 1358485
- ORCID : 0000-0002-0921-9952
Résumé
Experimental systems that faithfully replicate human physiology at cellular, tissue and organ level are crucial to the development of efficacious and safe therapies with high success rates and low cost. The development of such systems is challenging and requires skills, expertise and inputs from a diverse range of experts, such as biologists, physicists, engineers, clinicians and regulatory bodies. Kirkstall Limited, a biotechnology company based in York, UK, organised the annual conference, Advances in Cell and Tissue Culture (ACTC), which brought together people having a variety of expertise and interests, to present and discuss the latest developments in the field of cell and tissue culture and in vitro modelling. The conference has also been influential in engaging animal welfare organisations in the promotion of research, collaborative projects and funding opportunities. This report describes the proceedings of the latest ACTC conference, which was held virtually on 30th September and 1st October 2020, and included sessions on in vitro models in the following areas: advanced skin and respiratory models, neurological disease, cancer research, advanced models including 3-D, fluid flow and co-cultures, diabetes and other age-related disorders, and animal-free research. The roundtable session on the second day was very interactive and drew huge interest, with intriguing discussion taking place among all participants on the theme of replacement of animal models of disease.