Nonlinear optical and antimicrobial activity of N-acyl glycine derivatives
Résumé
The current paper provides a theoretical and experimental coupled study of synthesized N–octanoyl glycine and N–oleoyl glycine. The derivatives were characterized using nuclear magnetic resonance (1H and 13C NMR), liquid chromatography–mass spectrometry (LC-MS), Fourier–transform infrared (FT-IR), and ultraviolet–visible (UV–Vis) spectroscopy. The resulting N-acyl glycines were assessed for their in vitro antimicrobial activity. The experimental investigation is supported by a linear and nonlinear optical study based on DFT levels and shows that our glycine analogues get moderate hyperpolarizability (beta). The results of these glycines are of moderate amplitude, like those of amino acids. For this, several procedures have been discussed for achieving these values.