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Article Dans Une Revue Rapid Communications in Mass Spectrometry Année : 2011

Two-dimensional Fourier transform ion cyclotron resonance mass spectrometry: reduction of scintillation noise using Cadzow data processing

Résumé

In two-dimensional Fourier transform ion cyclotron resonance mass spectrometry (2D FTICR-MS), scintillation noise, caused mostly by fluctuations in the number of ions in the ICR cell, is the leading cause for errors in spectrum interpretation. In this study, we adapted an algorithm based on singular value decomposition and first introduced by Cadzow et al. (IEE Proceedings Pt. F 1987, 134, 69) to 2D FTICR-MS and we measured its performance in terms of noise reduction without losing signal information in the 2D mass spectrum.

Dates et versions

hal-04471949 , version 1 (21-02-2024)

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Maria A. van Agthoven, Marie-Aude Coutouly, Christian Rolando, Marc-André Delsuc. Two-dimensional Fourier transform ion cyclotron resonance mass spectrometry: reduction of scintillation noise using Cadzow data processing. Rapid Communications in Mass Spectrometry, 2011, 25 (11), pp.1609-1616. ⟨10.1002/rcm.5002⟩. ⟨hal-04471949⟩
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