This research examines the stakeholders’ impacts on ASEAN air carriers and airline strategies to interact back the business environment when associating with opening up the ASEAN Single Aviation Market among ten member countries. Our empirical study is based on the analysis of the primary interviews with 19 regional and international aviation experts. Results indicate that the primary stakeholders including customers, distributors, competitors, suppliers; and the broad environment including technological change, global political forces, legal forces and natural forces depict the most significant impacts on the strategies developed by ASEAN-region airlines.