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Communication Dans Un Congrès Année : 2022

De novo sequencing and assembly of complex genomes

Résumé

The introduction of short-reads technologies ten years ago, significantly increased the number of available genomes. Generally, these assemblies are incomplete and fragmented, and only a few of them are at the chromosome-scale. More recently, Oxford Nanopore sequencing technology was commercialized with the promise to sequence long DNA fragments (kilobases to megabases order) and then, by using efficient algorithms, provide assembly of high quality in terms of contiguity and completeness of the repetitive regions. This presentation will provide an overview of the capability of current technologies to generate chromosome-scale assemblies and describe some recent projects of plant and animal genomes.
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Dates et versions

hal-04443758 , version 1 (07-02-2024)

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  • HAL Id : hal-04443758 , version 1

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Jean-Marc Aury. De novo sequencing and assembly of complex genomes. reads2genpop : From sequence reads to genomes and populations, Sep 2022, Paris, Auditorium de la Grande Galerie de l’Evolution, France. ⟨hal-04443758⟩
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