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Article Dans Une Revue Blood Année : 2019

Description of a knock-in mouse model of JAK2V617F MPN emerging from a minority of mutated hematopoietic stem cells

Résumé

Key Points PF4iCre;JAK2 V617F/WT mice develop a full MPN that mimics polycythemia vera. The PF4iCre system induces JAK2V617F mutation in a small subset of HSC.

Dates et versions

hal-04429945 , version 1 (31-01-2024)

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Olivier Mansier, Badr Kilani, Amélie Guitart, Alexandre Guy, Virginie Gourdou-Latyszenok, et al.. Description of a knock-in mouse model of JAK2V617F MPN emerging from a minority of mutated hematopoietic stem cells. Blood, 2019, 134 (26), pp.2383-2387. ⟨10.1182/blood.2019001163⟩. ⟨hal-04429945⟩
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