Poster De Conférence Année : 2023

Mirusviruses: a complex evolutionary trajectory beyond realms

Résumé

The Varidnaviria and the Duplodnaviria are two very large cosmopolitan viral realms, comprising eukaryotic, bacterial, and archaeal viruses. Each is characterized by a distinct virion morphogenesis module and is hypothesized to have an ancient independent origin. The Duplodnaviria include the archaeal and bacterial Caudoviricetes, which are abundant in aquatic environments, and the animal-infecting Herpesvirales. On the other hand, the Varidnaviria comprise prokaryote-infecting Tectiliviricetes and other eukaryotic viruses, particularly the large and giant viruses of the Nucleocytoviricota phylum. By combining phylogenetics and metagenomic reconstructions, we recently identified and characterized over 100 genomes of a new viral clade related to both realms. These viruses, dubbed mirusviruses, possess the virion morphogenesis module of Herpesvirales but have more genes in common with Nucleocytoviricota, including most genes from the informational module. These chimeric attributes of Mirusviruses remain enigmatic, and their origin is unknown. Phylogenomic exploration and phylogenies of concatenated and single proteins highlight a complex evolutionary trajectory of these eukaryotic viruses.

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Dates et versions

hal-04394603 , version 1 (15-01-2024)

Identifiants

  • HAL Id : hal-04394603 , version 1

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Morgan Gaïa, Lingjie Meng, Antonio Fernandez-Guerra, Hiroyuki Ogata, Mart Krupovic, et al.. Mirusviruses: a complex evolutionary trajectory beyond realms. 5th Ringberg Symposium on Giant Virus Biology, Dec 2023, Tegernsee, Germany. ⟨hal-04394603⟩
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