The fundamental mechanisms of the Korotkoff sounds generation - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Science Advances Année : 2023

The fundamental mechanisms of the Korotkoff sounds generation

Résumé

Blood pressure measurement is the most widely performed clinical exam to predict mortality risk. The gold standard for its noninvasive assessment is the auscultatory method, which relies on listening to the so-called “Korotkoff sounds” in a stethoscope placed at the outlet of a pneumatic arm cuff. However, more than a century after their discovery, the origin of these sounds is still debated, which implies a number of clinical limitations. We imaged the Korotkoff sound generation in vivo at thousands of images per second using ultrafast ultrasound. We showed with both experience and theory that Korotkoff sounds are paradoxically not sound waves emerging from the brachial artery but rather shear vibrations conveyed in surrounding tissues by the nonlinear pulse wave propagation. When these shear vibrations reached the stethoscope, they were synchronous, correlated, and comparable in intensity with the Korotkoff sounds. Understanding this mechanism could ultimately improve blood pressure measurement and provide additional understanding of arterial mechanical properties.
Fichier principal
Vignette du fichier
Baranger et al_2023_The fundamental mechanisms of the Korotkoff sounds generation.pdf (1.67 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Licence : CC BY NC - Paternité - Pas d'utilisation commerciale

Dates et versions

hal-04384466 , version 1 (10-01-2024)

Identifiants

Citer

Jérôme Baranger, Olivier Villemain, Guillaume Goudot, Alexandre Dizeux, Heiva Le Blay, et al.. The fundamental mechanisms of the Korotkoff sounds generation. Science Advances , 2023, 9 (40), pp.eadi4252. ⟨10.1126/sciadv.adi4252⟩. ⟨hal-04384466⟩
14 Consultations
6 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More