Published trials of TACE for HCC are often not registered and subject to outcome reporting bias - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue JHEP Reports Innovation in Hepatology Année : 2021

Published trials of TACE for HCC are often not registered and subject to outcome reporting bias

Résumé

Background The Nutri-Score, a front-of-pack nutrition label, has been adopted in 2017 in France but its impact on low-income populations is unknown, and they are more at risk of having unhealthy diets. The present study assessed the effects of the Nutri-Score on the nutritional quality of purchasing intentions among low-income individuals, compared with the current French labelling situation: references intakes (RIs) and no label, using a three-arm parallel-group randomised controlled trial. Methods Low-income active adults from the NutriNet-Santé cohort (household income below €1200/month) were asked to perform a shopping task in an experimental online supermarket after being randomised in one of the three conditions (Nutri-Score, RIs or no labelling). The main outcome was the overall nutritional quality of the virtual shopping cart, assessed with the French-modified Food Standards Agency Nutrient Profiling System (FSAm-NPS), and secondary outcomes were the nutrient content of the shopping carts. 524 subjects were randomised, and 336 included in the analyses. Results The Nutri-Score resulted in the highest overall nutritional quality of the shopping cart, as reflected by a FSAm-NPS score (1.86 (SD 3.59) points) significantly lower (reflecting higher nutritional quality) than the RIs (3.21 (SD 4.14) points, p≤0.05) but not significantly lower than no label (2.60 (SD 3.09) points, p=0.3). The Nutri-Score also resulted into significantly lower contents in calories and saturated fatty acids in the shopping cart, compared with the RIs only (p≤0.05). Conclusion The implementation of the front of pack nutrition label Nutri-Score, adopted in France and in different European countries, appears to have the potential to encourage purchasing intentions of foods from higher nutritional quality among low-income individuals, compared with the RIs label promoted by food manufacturers. Trial registration number: NCT02769455
Fichier principal
Vignette du fichier
S2589555920301300.pdf (622.99 Ko) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-04369519 , version 1 (22-07-2024)

Licence

Identifiants

Citer

Jules Grégory, Perrine Créquit, Valérie Vilgrain, Isabelle Boutron, Maxime Ronot. Published trials of TACE for HCC are often not registered and subject to outcome reporting bias. JHEP Reports Innovation in Hepatology, 2021, 3 (1), pp.100196. ⟨10.1016/j.jhepr.2020.100196⟩. ⟨hal-04369519⟩
14 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More