We study labor-market discrimination of individuals with “specific” characteristics in Italy. We conduct a field experiment in two Italian cities: Rome and Milan, by sending “fake” CVs to real ads. We find that there is a strong penalty for homosexuals, i.e., about 30 % less chance to be called back compared to a heterosexual male and even more so if they are highly skilled. On the other hand, we find no penalty for homosexual females. We also find a beauty premium for females only but this premium is much lower when the “pretty” woman is skilled. Copyright Springer-Verlag Berlin Heidelberg 2015