Prevalence and significance of fragmented QRS complex in lead V<sub>1</sub> on the surface electrocardiogramof healthy athletes - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue EP-Europace Année : 2020

Prevalence and significance of fragmented QRS complex in lead V1 on the surface electrocardiogramof healthy athletes

Résumé

Aims Limited data exist concerning fragmented QRS complexes (fQRSs) on the surface electrocardiogram (ECG) of apparently healthy athletes. We aimed to study the prevalence and significance of fQRS in lead V-1 (fQRS(V1)), representing right ventricular (RV) activation, regarding training-induced RV morphological remodelling. Methods and results Between January 2017 and August 2019, 434 consecutive non-sedentary subjects underwent preparticipation cardiovascular screening, including a 12-lead ECG. Three hundred and ninety-three apparently healthy subjects were included, 119 of them were athletes (defined as performing >= 8 h/week for the last 6 months) and 274 were non-athletes. All athletes underwent two-dimensional transthoracic echocardiography. Fragmented QRS complex in lead V-1 pattern was defined as a narrow (<120 ms) and quadriphasic QRS complex in lead V-1. Fragmented QRS complex in lead V-1 was more frequent in athletes compared with non-athletes (22% vs. 5.1%, P < 0.001) and was independently associated with the athlete status [adjusted odds ratio (aOR) = 4.693, 95% confidence interval (95% CI) 2.299-9.583; P < 0.001], the endurance category (aOR = 2.522, 95% CI 1.176-5.408; P = 0.017), and age (aOR = 0.962, 95% CI 0.934-0.989; P = 0.007) in multivariate analysis. In the subgroup of athletes, fQRS(V1) was independently associated with mean RV outflow tract diameter (aOR = 1.458, 95% CI 1.105-1.923; P = 0.008) and age (aOR = 0.941, 95% CI 0.894-0.989; P = 0.017) in multivariate analysis. Conclusion Fragmented QRS complex in lead V1 is a newly described, frequent, ECG pattern in young and apparently healthy athletes and is associated with training-induced RV remodelling.

Dates et versions

hal-04329330 , version 1 (07-12-2023)

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Pierre Ollitrault, Arnaud Pellissier, Laure Champ-Rigot, Nicolas Junqua, Mathieu Chequel, et al.. Prevalence and significance of fragmented QRS complex in lead V1 on the surface electrocardiogramof healthy athletes. EP-Europace, 2020, 22 (4), pp.649--656. ⟨10.1093/europace/euaa037⟩. ⟨hal-04329330⟩
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