Objective Clinical Structured Examination (OSCE) is used to assess multiple competencies in medical pedagogy such as efficiently eliciting relevant clinical history from a patient. Clinical interviewing is done in a question and answer fashion, making it amenable to computer simulation. We introduce Chameleon, a framework to create virtual patients in an OSCE setting using the conversational agent platform Dialogflow CX. Our framework consists of a generic chatbot that is capable of answering most questions (in a classic non-specific clinical interview) and which can be expanded to capture any clinical presentation, e.g. a patient with backpain.