Photoplethysmography (PPG) is a non-invasive and cost-efficient optical technique used to assess blood volume variation inside the micro-circulation. PPG technology is widely used in a variety of clinical and non-clinical devices in order to investigate the cardiovascular system. One example of clinical PPG device is the pulse oxymeter, while non-clinical PPG devices include smartphones and smartwatches. Such a wide diffusion of PPG devices generates plenty of different PPG signals that differ from each other. In fact, intrinsic device characteristics strongly influence PPG waveform. In this paper we investigate transfer learning approaches on a Covolutional Neural Network based quality assessment method in order to generalize our model across different PPG devices. Our results show that our model is able to classify accurately signal quality over different PPG datasets while requiring a small amount of data for fine-tuning.Clinical relevance— A precise detection and extraction of high quality PPG segments could enhance significantly the reliability of the medical analysis based on the signal.