Article Dans Une Revue Scientific Data Année : 2022

An Open MRI Dataset For Multiscale Neuroscience

Résumé

Multimodal neuroimaging grants a powerful window into the structure and function of the human brain at multiple scales. Recent methodological and conceptual advances have enabled investigations of the interplay between large-scale spatial trends (also referred to as gradients) in brain microstructure and connectivity, offering an integrative framework to study multiscale brain organization. Here, we share a multimodal MRI dataset for Microstructure-Informed Connectomics (MICA-MICs) acquired in 50 healthy adults (23 women; 29.54 ± 5.62 years) who underwent high-resolution T1-weighted MRI, myelinsensitive quantitative T1 relaxometry, diffusion-weighted MRI, and resting-state functional MRI at 3 Tesla. In addition to raw anonymized MRI data, this release includes brain-wide connectomes derived from (i) resting-state functional imaging, (ii) diffusion tractography, (iii) microstructure covariance analysis, and (iv) geodesic cortical distance, gathered across multiple parcellation scales. Alongside, we share large-scale gradients estimated from each modality and parcellation scale. Our dataset will facilitate future research examining the coupling between brain microstructure, connectivity, and function. MICA-MICs is available on the Canadian Open Neuroscience Platform data portal (https:// portal.conp.ca) and the Open Science Framework (https://osf.io/j532r/).

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hal-04307118 , version 1 (25-11-2023)

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Jessica Royer, Raúl Rodríguez-Cruces, Shahin Tavakol, Sara Larivière, Peer Herholz, et al.. An Open MRI Dataset For Multiscale Neuroscience. Scientific Data , 2022, 9 (1), pp.569. ⟨10.1038/s41597-022-01682-y⟩. ⟨hal-04307118⟩
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