The need for an accurate description of the liquid composition is emerging in recently published studies on the interaction of droplets and flames. The selective release of species from a droplet surface into a reacting flow has been shown to impact the evolution of chemical reactions. However, preference has been given to hydrocarbons. Hydrophilic fuels were not explored enough to allow a broad perception of the importance of considering the multi-component description of liquid droplets in reacting flows. This may be justified by the limitations of the modeling strategies, which could not describe the simultaneous occurrence of evaporation and condensation for different species. Such limitations have been recently overcome by a new phase change model [1]. Given these aspects, this work investigates the impact of accurately describing the heat and mass transfers on droplets interacting with flames. Numerical simulations of freely propagating flames in droplet mists are conducted with a detailed chemistry description. Different scenarios focus on the impact of water addition in the gaseous or in the liquid phase. Results demonstrated that accounting for the multi-component phase change significantly impacts the flame speed. This is shown to be a consequence of the hydrophilic property of the chosen fuel, which allows the conversion from single-component to multi-component droplets, thus modifying the flame structure.