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Article Dans Une Revue American Journal of Physiology - Cell Physiology Année : 2023

Revisiting specific force loss in human permeabilized single skeletal muscle fibers obtained from older individuals

Résumé

Whether specific force (SF) decreases with advancing age in human single skeletal muscle fibers is uncertain. Equivocal published findings may be due to the different physical activity levels of the elderly cohorts studied and/or different chemical solutions used to measure force. We compared single fiber SF between young adults, elderly cyclists, and hip fracture patients (HFP) using two solutions. The solution used significantly affected force and revealed a difference in sensitivity of HFP muscle fibers.

Dates et versions

hal-04302679 , version 1 (23-11-2023)

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Michaeljohn Kalakoutis, Ross Pollock, Norman Lazarus, Robert Andrew Atkinson, Marc George, et al.. Revisiting specific force loss in human permeabilized single skeletal muscle fibers obtained from older individuals. American Journal of Physiology - Cell Physiology, 2023, 325 (1), pp.C172-C185. ⟨10.1152/ajpcell.00525.2022⟩. ⟨hal-04302679⟩
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