Clustering and temporal organization of sleep spindles underlie motor memory consolidation - Archive ouverte HAL Accéder directement au contenu
Pré-Publication, Document De Travail Année : 2022

Clustering and temporal organization of sleep spindles underlie motor memory consolidation

Résumé

Abstract Sleep benefits motor memory consolidation, which is mediated by sleep spindle activity and associated memory reactivations during non-rapid eye movement (NREM) sleep. However, the particular role of NREM2 and NREM3 sleep spindles and the mechanisms triggering this memory consolidation process remain controversial. Here, simultaneous electroencephalographic and functional magnetic resonance imaging (EEG-fMRI) recordings were collected during night-time sleep following the learning of a motor sequence task. Adopting a time-based clustering approach, we provide evidence that spindles iteratively occur within clustered and temporally organized patterns during both NREM2 and NREM3 sleep. However, the clustering of spindles in trains is related to motor memory consolidation during NREM2 sleep only. Altogether, our findings suggest that spindles’ clustering and rhythmic occurrence during NREM2 sleep may serve as an intrinsic rhythmic sleep mechanism for the timed reactivation and subsequent consolidation of motor memories, through synchronized oscillatory activity within a subcortical-cortical network involved during learning.

Dates et versions

hal-04300618 , version 1 (22-11-2023)

Identifiants

Citer

Arnaud Boutin, Ella Gabitov, Basile Pinsard, Arnaud Boré, Julie Carrier, et al.. Clustering and temporal organization of sleep spindles underlie motor memory consolidation. 2023. ⟨hal-04300618⟩
9 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More