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Conference Papers Year : 2023

Lower respiratory tract involvement in recurrent respiratory papillomatosis in a multicentric cohort study

Thomas Maitre
Minh Triet Ngo
  • Function : Author
Nicolas Guibert
Clement Fournier
  • Function : Author
M Matar
Arnaud Bourdin
Thomas Egenod
Delphine Wermert
  • Function : Author
Nicolas Favrolt
  • Function : Author
Olivia Freynet
  • Function : Author
Valérie Gounand
  • Function : Author
Raphaël Borie
  • Function : Author
  • PersonId : 1123489
Raffaele Caliandro
  • Function : Author
Jean Francois Boitiaux
  • Function : Author
Julie Mankikian
  • Function : Author
Juliette Camuset
  • Function : Author
Vincent Cottin
Jean-Michel Vergnon
  • Function : Author
  • PersonId : 867323
Jacques Cadranel

Abstract

Recurrent respiratory papillomatosis (RRP) is a rare disease due to chronic Human Papillomavirus infection, occurring in childhood (JoRRP) or adults (AoRRP). PRR characterized by progressive obstruction papillomas mostly affecting upper airway and more rarely lower tract (LRT), including lungs. This study describes the characteristics of Jo AoRRP LRT at adulthood. French Quebecers’ national retrospective clinical, histological, therapeutic prognostic with RRP-LRT. Among 67 patients (pts), 17 (25%) were JoRRP 50 (75%) AoRRP. The mean age diagnosis was 5 yrs for 54 ENT involvement observed all 23 (46%) Lung 11 (76%) 2 (4%) Mean latency duration between lung 26 4 CT-scan findings cysts pts (74%) nodules/mass (13%), predominating lobes. 13 (19%) had malignant transformation squamous cell carcinoma trachea (n=3) (n=10). Associated factors female gender, JoRRP, HPV-11, repeated desobstruction tracheostomy while they HPV-16 presence involvements transformation. Overall mortality 9%, form, being (pandlt
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Dates and versions

hal-04286396 , version 1 (15-11-2023)

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Thomas Maitre, Romy Ratsihorimanana, Mathieu Dusselier, Gilles Mangiapan, Minh Triet Ngo, et al.. Lower respiratory tract involvement in recurrent respiratory papillomatosis in a multicentric cohort study. ERS International Congress 2023 abstracts, Sep 2023, Milano, Italy. pp.PA427, ⟨10.1183/13993003.congress-2023.pa427⟩. ⟨hal-04286396⟩
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