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Article Dans Une Revue Biomedical optics express Année : 2021

Polarimetric visualization of healthy brain fiber tracts under adverse conditions: ex vivo studies

Omar Rodríguez-Núñez
Philippe Schucht
  • Fonction : Auteur
Ekkehard Hewer
  • Fonction : Auteur
Angelo Pierangelo

Résumé

We suggest using the wide-field imaging Mueller polarimetry to contrast optically anisotropic fiber tracts of healthy brain white matter for the detection of brain tumor borders during neurosurgery. Our prior studies demonstrate that this polarimetric imaging modality detects correctly the in-plane orientation of brain white matter fiber tracts of a flat formalin-fixed thick brain specimen in reflection geometry [ IEEE Trans. Med. Imaging 39 , 4376 ( 2020 ) 10.1109/TMI.2020.3018439 ]. Here we present the results of ex vivo polarimetric studies of large cross-sections of fresh calf brain in reflection geometry with a special focus on the impact of the adverse measurement conditions (e.g. complex surface topography, presence of blood, etc.) on the quality of polarimetric images and the detection performance of white matter fiber tracts and their in-plane orientation.

Dates et versions

hal-04286319 , version 1 (15-11-2023)

Identifiants

Citer

Omar Rodríguez-Núñez, Philippe Schucht, Ekkehard Hewer, Tatiana Novikova, Angelo Pierangelo. Polarimetric visualization of healthy brain fiber tracts under adverse conditions: ex vivo studies. Biomedical optics express, 2021, 12 (10), pp.6674. ⟨10.1364/BOE.439754⟩. ⟨hal-04286319⟩
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