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Article Dans Une Revue (Article De Synthèse) La Presse Médicale Année : 1992

[Molecular bases of cardiac aging].

Résumé

The total volume occupied by myocytes in the heart decreases with age, and this is accompanied by a loss of myocytes, by hypertrophy and, to a lesser extent, by hyperplasia of the remaining myocytes. There are differences between ventricles: the right ventricular myocytes have a greater capacity for replication than those of the left ventricle. The expression of genes coding for the 2 principal contractile proteins (myosin and actin) is modified, and there are strong resemblances between the phenotype of the aged heart and that of an adult heart with haemodynamic overload.
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Dates et versions

hal-04275777 , version 1 (08-11-2023)

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  • HAL Id : hal-04275777 , version 1
  • PUBMED : 1409472

Citer

L Carrier, Catherine Chassagne, K Boheler, K Schwartz. [Molecular bases of cardiac aging].. La Presse Médicale, 1992, 21 (26), pp.1196-8. ⟨hal-04275777⟩
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