Iron‐catalyzed Hydrosilylation of Secondary Carboxamides Chemoselective Access to Aldimines
Résumé
This contribution described the chemoselective reduction of secondary carboxamides to aldimines. To perform such challenging transformation, we reported a catalyzed hydrosilylation using Fe(CO)4(IMes) [IMes=1,3‐bis (2,4,6‐trimethylphenyl) imidazol‐2ylidene] as catalyst, diphenylsilane reductant under UV irradiation (365 nm) at room temperature for 16 h. Aldimines were then obtained, after basic quench, in 40‐83% isolated yields. transformation was unprecedented iron.
Domaines
Catalyse
Fichier principal
ChemCatChem - 2023 - Wu - Iron‐catalyzed Hydrosilylation of Secondary Carboxamides Chemoselective Access to Aldimines.pdf (2.28 Mo)
Télécharger le fichier
Origine | Publication financée par une institution |
---|