Challenges and Breakthroughs in Z‐Enantioselective Olefin Metathesis
Résumé
Asymmetric Olefin Metathesis (AOM) represents a highly versatile synthetic tool to lead relevant chiral building blocks with excellent enantiopurity. As the Z ‐alkene moiety is ubiquitous in wide range of natural products, development catalysts which are able control both ‐selectivity and enantioselectivity metathesis transformations high demands. This review aims provide comprehensive overview covering all breakthroughs accomplished field challenging ‐enantioselective olefin metathesis, interest total synthesis complex molecules.