The Discovery of VB-Gy Filmogen Glycerol Should Revolutionize Hemorrhoidal Treatment in the Future - Archive ouverte HAL Accéder directement au contenu
Autre Publication Scientifique Journal of Clinical Trials and Research Année : 2018

The Discovery of VB-Gy Filmogen Glycerol Should Revolutionize Hemorrhoidal Treatment in the Future

Gisela da Silva Borges
Ravi Shrivastava

Résumé

Hemorrrhoids result from dilation of the submucosal vascular tissue in the distal anal canal. These dilated blood vessels may remain inside the anal canal (internal hemorrhoids) or may protrude outside the anus (external hemorrhoids). Persistent vascular dilation may lead to severe inflammation with associated pain and discomfort. Anti- and pro-inflammatory cytokines flood hemorrhoidal surface but if vascular oedema is not removed, inflammation persists and hemorrhoids become chronic. Theoretically, it should not be difficult to reduce vascular oedema and the concentration of pro-inflammatory cytokines from the hemorrhoidal surface, but even modern medicine is not capable of finding a drug which can act simultaneously on vascular oedema, inflammation, pain, and hydration without serious side effects. A few scientists in France imagined using a non-irritant and highly osmotic liquid solution as a topical film over the hemorrhoidal surface to drain out oedema fluid and to clean the hemorrhoidal surface with the outcoming liquid flow. They observed that minimizing oedema and cleaning away inflammatory cytokines through a mechanical and totally safe process produces excellent results within a few days. Being topical, such a treatment cannot induce any side effects. The authors are convinced that such a simple, safe, and multi-target therapeutic approach should revolutionize future treatment of hemorrhoids.
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Dates et versions

hal-04258463 , version 1 (05-12-2023)

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  • HAL Id : hal-04258463 , version 1

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Gisela da Silva Borges, Ravi Shrivastava, Monika Rousse. The Discovery of VB-Gy Filmogen Glycerol Should Revolutionize Hemorrhoidal Treatment in the Future. 2018, pp.J Clin Trials Res, 1(1): 3-4. ⟨hal-04258463⟩
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