Nucleic‐Acid‐Templated Synthesis of Smart Polymer Vectors for Gene Delivery - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue ChemBioChem Année : 2023

Nucleic‐Acid‐Templated Synthesis of Smart Polymer Vectors for Gene Delivery

Résumé

Nucleic acids are information‐rich and readily available biomolecules, which can be used to template the polymerization of synthetic macromolecules. Here, we highlight the control over the size, composition, and sequence one can nowadays obtain by using this methodology. We also highlight how templated processes exploiting dynamic covalent polymerization can, in return, result in therapeutic nucleic acids fabricating their own dynamic delivery vector – a biomimicking concept that can provide original solutions for gene therapies.

Domaines

Chimie organique
Fichier principal
Vignette du fichier
ChemBioChem - 2023 Garcia_Ulrich_Nucleic‐Acid‐Templated_2023.pdf (7.85 Mo) Télécharger le fichier
Origine Publication financée par une institution
Licence

Dates et versions

hal-04255029 , version 1 (23-10-2023)

Licence

Identifiants

Citer

José García Coll, Sébastien Ulrich. Nucleic‐Acid‐Templated Synthesis of Smart Polymer Vectors for Gene Delivery. ChemBioChem, 2023, 24 (19), pp.e202300333. ⟨10.1002/cbic.202300333⟩. ⟨hal-04255029⟩
4 Consultations
9 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More