The estrogen-related receptors and the adipocyte - Archive ouverte HAL
Article Dans Une Revue Hormone Molecular Biology and Clinical Investigation Année : 2013

The estrogen-related receptors and the adipocyte

Jean-Marc Vanacker
  • Fonction : Auteur

Résumé

Abstract The estrogen-related receptors (ERRα, β, and γ) are orphan members of the nuclear receptor superfamily. ERRα and γ are highly expressed in tissues displaying elevated energy demands and are involved in several aspects of energetic metabolism, which they regulate mostly in association with members of the PGC-1 coactivator family. These activities have mostly been documented in the liver, heart, or skeletal muscle. ERRα and γ are also highly expressed in adipocytes. Their precise roles in this cell type are less documented, although published data indicate that they contribute to cell differentiation as well as functionality. This review describes these activities.
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Dates et versions

hal-04242220 , version 1 (14-10-2023)

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Julie Carnesecchi, Jean-Marc Vanacker. The estrogen-related receptors and the adipocyte. Hormone Molecular Biology and Clinical Investigation, 2013, 14 (3), pp.15108-15113. ⟨10.1515/hmbci-2013-0020⟩. ⟨hal-04242220⟩
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