Development of targeted photodynamic therapy drugs by combining a zinc phthalocyanine sensitizer with TSPO or EGFR binding groups: the impact of the number of targeting agents on biological activity - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Organic & Biomolecular Chemistry Année : 2023

Development of targeted photodynamic therapy drugs by combining a zinc phthalocyanine sensitizer with TSPO or EGFR binding groups: the impact of the number of targeting agents on biological activity

Isabelle Toubia
  • Fonction : Auteur
Christophe Nguyen
Mélanie Onofre
  • Fonction : Auteur
Morgane Daurat
Corentin Gauthier
Magali Gary-Bobo
Marwan Kobeissi

Résumé

This study investigates the implementation of multivalent effect for PDT to enhance the selectivity of the treatment.
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Dates et versions

hal-04235573 , version 1 (10-10-2023)

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Citer

Isabelle Toubia, Christophe Nguyen, Stéphane Diring, Mélanie Onofre, Morgane Daurat, et al.. Development of targeted photodynamic therapy drugs by combining a zinc phthalocyanine sensitizer with TSPO or EGFR binding groups: the impact of the number of targeting agents on biological activity. Organic & Biomolecular Chemistry, 2023, 21 (32), pp.6509-6523. ⟨10.1039/D3OB00565H⟩. ⟨hal-04235573⟩
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